Medication profile



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Acetaminophen

MEDICATION PROFILE

Medication (Trade & generic) Tylenol; acetaminophen
Classification antipyretics; nonopioid analgesics

Mechanism of Action

Indications &
Expected Outcome



Side Effects/Adverse Reactions

Nursing Responsibilities

Instructions for PO administration:

Administer with a full glass of water.


May be taken with food or on an empty stomach
Reconstitution instructions:
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Instructions for intermittent IV administration:
--
Instructions for direct IV administration:
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Inhibits synthesis of prostaglandins that may serve as mediators of pain and fever, primarily in the CNS.

Has no significant anti-inflammatory properties or GI toxicity.



Indications:


Treatment of:
Mild pain
Fever
Expected Outcome:

Relief of mild to moderate pain.


Reduction of fever.



Common (italics):


CNS: agitation, anxiety, headache, fatigue, insomnia
CV: hypertension, hypotension
Derm: rash, urticaria
F and E: hypokalemia
GI: constipation (↑ in children), ↑ liver enzymes, nausea, vomiting
GU: renal failure (high doses/chronic use)
Hemat: neutropenia, pancytopenia
MS: muscle spasms, trismus
Resp: atelectasis (↑ in children), dyspnea


Life threatening (bold):
Acute Generalized Exanthematous, Stevens-Johnson Syndrome. Toxic Epidermal Necrolysis, Hepatotoxicity (increased doses)

  • Assess overall health status and alcohol usage before administering acetaminophen.




  • Assess for rash periodically during therapy. May cause Stevens-Johnson syndrome.




  • Pain: Assess type, location, and intensity prior to and 30–60 min following administration.




  • Fever: Assess fever; note presence of associated signs (diaphoresis, tachycardia, and malaise).




Revised 1-10-13 Student:

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