Explain how a single base-pair mutant in dna can alter the structure and, in some cases, the function of a protein. (b) Explain



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Timed Free Response Essay Mutations

1. Certain human genetic conditions, such as sickle cell anemia, result from single base-pair mutations in DNA.

(a) Explain how a single base-pair mutant in DNA can alter the structure and, in some cases, the function of a protein.

(b) Explain, using a specific example, the potential consequences of the production of a mutant protein to the structure and function of the cells of an organism.

(c) Describe how the frequency of an allele coding for a mutant protein may increase in a population over time.

Total /7=____


General Rubric

Criteria A

Supporting Details A (1pt)

Supporting Details A (1pt)

Supporting Details A (1pt)

Total=3

Explain how a single base-pair mutant in DNA can alter the structure and, in some cases, the function of a protein

a.) Explanation of what single base-pair mutations are

b.)Explanation of how a single base-pair mutation can affect the structure of a protein.

c.) Describe an example of a base-pair mutation.







Criteria B (2pts)

Supporting Details B (1pt)

Supporting Details B (1pt)

Total=2

Explain, using a specific example, the potential consequences of the production of a mutant protein to the structure and function of the cells of an organism.


d.) Provide a specific example of consequences of the production of a mutant protein

e.) Explain why or how a mutation can affect the function of the cells of an organism






Criteria C (2pts)

Supporting Details B (1pt)

Supporting Details B (1pt)

Total=2

(c) Describe how the frequency of an allele coding for a mutant protein may increase in a population over time.


f) Provide an explanation of how the frequency of an allele coding for a mutant protein may increase in a population over time.


g) Explain a hypothetical or real example of mutant protein increasing in a population over time.





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