Basal layer of epidermis consists of



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В. Chlamydia trachomatis 


С. Neisseria gonorrhoeae

D. Trichomonas vaginalis


Е. Gardnerella vaginalis
Acanthosis is:

А) loss of connections between epitheliocytes;

В) thickening of corneous layer;

С) thickening of granular layer;

D) incomplete keratinization of cells;

Е) increased number of cell layers in spinous layer. ✔


Which of the following is not a complication of trichomoniasis in men?

А. Balanoposthitis

В. Colliculitis

С. Vaginitis

D. Epididymitis

Е. Vesiculitis
Spot is:

А) skin defect within hypodermis;

В) deep skin defect;

С) linear skin defect;

D) skin thickening with intensification of its pattern;

Е) local change in skin color ✔


In case of gonorrheal urethritis, all medicines should be prescribed, except:

A. Tetracycline

B. Macrolides

C. Imidazole✔

D. Fluoroquinolones

E. Cephalosporins

Exfoliation is:

А) desquamation of cells from the surface of epidermis ✔

В) migration of epitheliocytes;

С) apoptosis of keratinocytes;

D) proliferation of epitheliocytes;

Е) intensive cell division.


With which disease should differential diagnosis of pityriasis versicolor be conducted?

A. Lichen ruber planus

B. Psoriasis

C. Secondary fresh syphilis ✔

D. Duhring’s dermatosis

E. Pemphigus


All the following are used for diagnosis of gonorrhea, except:

A. Cultural method

B. Bacterioscopic investigation

C. Two-glass Thompson’s test

D. Histological method ✔

E. Provocation test


It is not referred to secondary morphological elements:

А) bulla ✔

В) crust;

С) excoriation;

D) lichenification;

Е) vegetation.


Which of the following drugs is referred to antifungal antibiotics?

A. Retarpen

B. Cycloferon

C. Nerobol

D. Bicillin-5

E. Orungal ✔


Factors contributing to transformation of fresh trichomoniasis into chronic form:
А. Exacerbation of chronic cystitis

В. Irrational treatment ✔

С. Always after fresh form

D. Exacerbation of other chronic diseases

Е. Exacerbation of chronic prostatitis
Acantholysis is:

А) thickening of corneous layer;

В) thickening of granular layer;

С) loss of connections between epitheliocytes; ✔

D) intercellular swelling;

Е) increased number of cell layers in spinous layer.


An agent of erythrasma is:

А.Trichophyton mentagrophytes

B. Еpidermophyton floccosum

C. Epidermophyton stockdaleae

D. Corinebacteria tenuis Castellani

E. Corinebacteria fluorescens erythrasmae ✔


On bacterioscopic examination of patients with acute gonorrhea, we detect:

А. Gonococci located extracellularly, little amount of leukocytes

В. Streptococci, staphylococci, yeasts, squamous epithelium

С. Gonococci located intracellularly and extracellularly, a large amount of leukocytes

D. Trichomonas, little amount of gonococci located inside trichomonas, little amount of leukocytes
Е. Leukocytes, yeasts, epithelium
All the following are types of hemorrhagic spots, except:

А) purpura;

В) roseole ✔

С) petechia;

D) ecchymosis;

Е) vibex.


Indicate diagnostic test which confirms diagnosis of microsporia of the scalp:

A. Appearance of bullae in application test with 50% potassium iodide ointment

B. Symptom of “bloody dew” on scratching

C. Brocq test

D. Acantholytic cells in impression smears

E. Fluorescence of lesion foci in smaragd color in the rays of a Wood’s luminescent lamp ✔


Erosion is:

А) skin defect within epidermis; ✔

В) deep skin defect;

С) linear skin defect;

D) skin thickening with intensification of its pattern;

Е) local change in skin color.


Microsporia of the scalp is referred to the group of

A. Keratomycoses

B. Dermatomycoses ✔

C. Pseudomycoses

D. Candidiasis

E. Deep mycoses


Excoriation is:

А) skin defect within epidermis;

В) thick fibrous connective tissue growths with lesion of the dermis and often underlying tissues;

С) deep skin defect within skin proper;

D) skin defect, which appeared due to scratching ✔

Е) impairment of skin pigmentation, which appeared due to resolution of morphological rash elements.


For which mycosis is the symptom of “honey combs” typical?

A. Pityriasis versicolor

B. Microsporia of the smooth skin

C. Microsporia of the scalp

D. Deep tinea corporis

E. Deep trichophytosis capitis ✔

Secondary spot is:

А) skin defect within epidermis;

В) thick fibrous connective tissue growths with lesion of the dermis and often underlying tissues;

С) deep skin defect within skin proper;

D) skin defect, which appeared due to scratching;

Е) impairment of skin pigmentation, which appeared due to resolution of morphological rash elements ✔


Which agents are used for treatment of microsporia of the scalp?

A. Gioxison ointment

B. Erythromycin ointment

C. Salicylic ointment

D. Griseofulvin ✔

E. Dermovate

A mother brought a 6-year old girl to a doctor with complains of facial rash, which had appeared 5 days before. Objectively: several bullae, size 0.5-1.5 cm in diameter with a thin loose cover, filled with serous cloudy exudates, which are located on hyperemic swollen base, are observed on facial skin. Also, erosions with serous purulent fluid exudates and thick honey-yellow crusts are noticed in lesion foci. Make clinical diagnosis.

А. contact dermatitis

В. Children eczema

С. herpes

D. impetigo vulgaris ✔

Е. candidiasis

Compile plan for examination and treatment.
A 65-year old patient complains of skin rash in the region of moustache and beard which has been present for the last 3 years. He was treated with natural medicines with periodic improvement. Objectively: tiny abscesses, resembling millet grain found in follicle shaft, are located in the region of moustache and beard, skin in the focus is infiltrated, swollen, with bluish tint. Drops of yellow-green pus appear from dilated hair follicles during pressing on infiltrate. General condition is not impaired. Which diagnosis is the most likely?

Який діагноз найбільш імовірний?

А. Allergic dermatitis

В. Acne vulgaris

С. Sycosis vulgaris ✔

D. Erysipelas of the face

Е. Carbuncle

Plan of examination.


A patient with multiple spots, which appeared after summer season, consulted a dermatologist. Spots are of various configurations and sizes, from light-beige to yellow-brown color. Which type of rashes, in your opinion, does this patient have?

А) genuine polymorphic;

В) monomorphic; ✔

С) exomorphic;

D) non-genuine polymorphic;

Е) follicular.

Name all types of spots that you know.
Patient D., 49 years old, was admitted to inpatient department complaining of rash on the trunk skin, tenderness in the oral cavity during eating, feeling of sickness. Objectively: bullae with transparent content, red erosions of various sizes, on the periphery of which are remnants of coverings of bullae, wine-red crusts are present on unchanged skin of the trunk. Erosive surfaces with dark grey plaque and vegetations are visualized in axillary folds. Red erosions of various sizes with remnants of coverings are present on the oral mucosa.

А. Vegetative pemphigus ✔

В. Herpetiform dermatosis (Duhring’s disease)

С. Pemphigus vulgaris

D. Exudative erythema multiforme

Е. Herpes

Which additional methods of examination should be performed for confirmation of diagnosis?
A patient, 68 years old, complains of rash and itching on the skin of the left shin. Objectively: trophic ulcer is visualized on the skin of the left shin. Skin around the defect is red and swollen, in some places single yellowish crusts and weeping are observed. Borders of the focus of damage are distinct. Which diagnosis is the most likely in this case?

А. Skin tuberculosis;

В. Allergic dermatitis;

С. Seborrheic eczema;

D. Microbial eczema; ✔

Е. Ecthyma vulgaris.

Compile treatment plan for this patient.
A female patient, 27 years old, presented with complaints of itching, skin rash on the trunk and extremities. She linked the disease to nervous stress. Local status: miliary papulae of pearl color, merged in the form of lace, are observed on oral mucosa. Lenticular polygonal papulae of pink-violet color with waxy surface and umbilicate depression in the center are visualized on the skin of the trunk and flexor surfaces of the extremities. Initial diagnosis?

А) Lichen ruber planus; ✔

В) Extensive psoriasis;

С) Molluscum contagiosum;

D) Lupus erythematosus;

Е) Flat warts.

Diagnostic criteria to make final and differential diagnoses.
In a 40-year old patient D., erosions on oral mucosa and bullae on the chest skin appeared, which suddenly transformed into erosions. He had been taking antibiotics for 2 weeks, but improvement was not observed. Objectively: round bright erosions approx. 2-3 cm in diameter and several soft bullae are on the oral mucosa and the chest. Exfoliation of epidermis is observed on pulling of covering border with a pincers.

Which disease is associated with this clinical picture?

А. Pemphigus vulgaris ✔

В. Duhring’s dermatosis

С. Herpes zoster

D. Herpes

Е. Eczema

Administer treatment to this patient.


In patient Sh., 51 years old, numerous papulopustular rashes are present on face skin. He associates the disease with frequent attacks of cholelithiasis. Dermatologist made diagnosis: Acne rosacea. Which analysis should be administered to make diagnosis of acne rosacea?

А. Blood analysis for Le-cells

В. Analysis of rash for detection of Demodex folliculorum ✔

С. Blood analysis for toxoplasmosis

D. Blood analysis for detection of Treponema Pallidum

Е. Analysis of rash for detection of itch mite

Which external remedies are used in treatment? Write out prescription of medicine.
A 60-year old patient complains of skin rash on the right shin, acute and burning pain, weakness, fever 390C. She has been ill for 2 days. Objectively: Bright-red erythema and swelling is present on the skin of the left shin. It is hot to touch, with irregular contour resembling body of flame. Your diagnosis?

А. Contact dermatitis

В. Erysipelas ✔

С. Microbial eczema

D. allergic dermatitis

Е. Thrombophlebitis

Compile treatment plan.
A patient consulted a doctor complaining of discharge from the urethra and painful urination. Objectively: sponge of the outer orifice of the urethra is distinctly hyperemic, swollen, purulent discharge is of yellow-green color in large amount. Your initial diagnosis?

А. Chlamydiosis

В. Gonorrhea✔

С. Mycoplasmosis

D. Gardnerella infection

Е. Candidosis

1. Verification of initial diagnosis.

2. Administration of treatment.


A man, 32 years old, consulted a dermatologist complaining of rash and itching. Nausea, vomiting, diarrhea, fever appeared after visiting restaurant. Papulae and spots are observed on extensor surfaces of the extremities. What is your initial diagnosis?

А. Simple contact dermatitis;

В. Acute eczema;

С. Urticaria;

D. Allergic contact dermatitis;

Е. Toxicodermia. ✔

Prescribe treatment to this patient.
A 59-year old woman was admitted to inpatient department complaining of rash on the trunk skin, itching, and general weakness. Objectively: bullae covered with crusts with tendency to grouping, are present on erythematous background on the skin of the abdomen, back, and face. Pathohistological data: subepidermal bullae, a considerable amount of eosinophils is in the bullae content. Which initial diagnosis can be made?

А. Vegetative pemphigus

В. Herpetiform dermatitis (Duhring’s disease) ✔

С. Pemphigus vulgaris

D. Exudative erythema multiforme

Е. Herpes

Which diagnostic tests should be performed to make final diagnosis?
A 3-month old child was admitted to inpatient treatment for otitis media. A pediatrician consulted a dermatologist for rash on the back and buttocks, temperature 380C. Objectively: numerous solid nodes, size from a pea to a hazel nut, dark red color are on the skin of the nape of the neck, back and buttocks. Yellow-green thick pus discharges from some nodes. The child is asthenic, not properly cared for. The father has active pulmonary tuberculosis.

Initial diagnosis.

А. hydradenitis

В. furunculosis

С. Multiple abscesses (pseudofurunculosis) ✔

D. vegetative pemphigus

Е. skin tuberculosis

Compile treatment plan.


A mother of a 7-year old girl consulted a dermatologist, complaining of rash on a child’s facial skin, which had appeared 3 days before, intensive itching. Objectively: bullae, size 0.3-1.0 cm in diameter with a thin loose cover, filled with serous cloudy exudates, located on hyperemic background, erosions with purulent exudates, honey-yellow crusts are found on facial skin. Your diagnosis:

А. dermatitis

В. Children eczema

С. herpes

D. impetigo vulgaris ✔

Е. Allergic dermatitis

Compile a plan of curative and preventive measures.
A patient, 19 years old, consulted a dermatologist, complaining of skin itching, which is worse at night. She has been suffering for 2 weeks. Pinpoint papules, excoriations are observed on the skin of the hands, papulovesicles are located in pairs in abdominal region. Which diagnosis should be made?

А. Allergic dermatitis

В. Scabies ✔

С. Acne rosacea

D. Microbial eczema

Е. Pediculosis of the trunk

Conduct differential diagnostics of this disease.
Female patient, 43 years old, presented with complaints of skin rash on both shins. Local condition: pink-bluish plaques, covered with corneous masses, densely packed, are observed on extensor surfaces of the shins. Polygonal lenticular papulae with umbilicate depression in the center and waxy luster are found around plaques. Your previous diagnosis?

А) Molluscum contagiosum;

В) Lichen ruber planus; ✔

С) Psoriasis;

D) Verrucous skin tuberculosis;

Е) Flat warts.

Give clinical diagnosis and treatment plan for the patient.
6. A 25-year old patient complains of rash on perineum skin, itching, burning, and pain in this region. She has been suffering for 1.5 weeks after she felt discomfort after depilation. In anamnesis – FoxFordyce disease.

Objectively: redness, painful nodes, size of a pea, are present on the skin of the perineum, in some places the nodules merge. Your initial diagnosis?

А. Ordinary sycosis

В. Hydradenitis ✔

С. eczema

D. contact dermatitis

Е. Pubic pediculosis

Perform differential diagnostics.


A grandmother brought a 5-year old child for out-patient examination with complaints of rash on the facial skin. Objectively: phlyctenae, diameter from 1 to 3 cm with cloudy content are present of face skin in the mouth region; a thin bright-red stripe of inflamed skin, erosions, crusts of yellow color are observed on the periphery of phlyctenae.

Your initial diagnosis?

А. Streptococcal impetigo ✔

В. Acne vulgaris

С. Face eczema

D. dermatitis

Е. herpes zoster

Compile plan of pathogenic treatment.
A 40-year old patient complains of fungiform tumor-like growth on the skin of vermillion border, which appeared throughout 3 weeks. Piercing preceded appearance of the growth. Clinically: tiny lobular tumor on a pedicle, size of a pea, globular form, soft consistency, dark red color with numerous vessels, which are easily injured and bleed. Your initial diagnosis?

А. melanoma

В. Botryomycoma ✔

С. Skin tuberculosis

D. verruca vulgaris

Е. Metastasis of a malignant tumor of internal organs

Conduct differential diagnosis.

In patient A., 7 years old, infiltrate regions of various sizes and moderately pink color, covered with numerous papular elements, excoriations on the skin of the trunk and extremities, are visualized. Dermographism is white. She has been suffering since early childhood. Nervous stress precedes exacerbation of pathological process. Which disease is meant?

А. Allergic dermatitis;

В. Eczema;

С. Urticaria;

D. Contact dermatitis;

Е. Atopic dermatitis.✔

Describe principles of treatment and prevention of this disease.


Patient B., 57 years old, complains of appearance of numerous bullae on the skin of the trunk, back, and chest. The bullae are soft, large, with serous content. After lancing, erosions form, which slowly epithelize. Erosions are also observed on the oral mucosa, thus, the process of eating is painful. Acantholytic cells are detected in impression smears from the base of erosions. Which initial diagnosis may be made in this case?

А. Eczema

В. Pemphigus vulgaris ✔

С. Allergic dermatitis

D. Lichen ruber planus (Bullous form)

Е. Exudative erythema multiforme

Write a treatment plan for this patient.
A patient consulted a doctor complaining of slight discharge from the urethra, dull pain in the perineum, which worsens during defecation, as well as lowered erection and accelerated ejaculation. It is known from the anamnesis that several years before the patient used large doses of antibiotics several times as a self-treatment after accidental sexual contacts. Gonococci, trichomonas and other bacteria were not detected in smears and culture of the discharge. Which disease is meant?

А. Chronic urethritis

В. Chronic prostatitis✔

С. Proctosigmoiditis

D. Periproctitis

Е. Chlamydial urethritis

1. Explanation of the chosen diagnosis.

2. Further tactics.


A 23-year old woman has been ill for 3 years, when she noticed for the first time a painful and solid enlargement, size of a pea, on the skin of the buttocks. In 4-5 days, a purulent shaft discharged from this node. Similar rashes appeared 203 times a year. She suffers from diabetes mellitus, type I. Your diagnosis?

А. furuncle

В. hydradenitis

С. chronic furunculosis ✔

D. carbuncle

Е. Herpes, type I

Tactics of treatment.

A 7-day old boy is staying in maternity home for rash on the skin of the trunk, upper and lower extremities. A child’s temperature is 37.50C. Objectively: bullae, with diameter 1.0-1.5 cm, cloudy content, and loose cover are on the skin of the trunk, upper and lower extremities, and buttocks. Palms and soles are not affected. Skin in the region of bullae is not infiltrated, slightly hyperemic.

Initial diagnosis?

А. Chicken pox

В. Epidemic pemphigus ✔

С. Children eczema

D. syphilitic pemphigus

Е. Herpetic infection

Tactics of examination and treatment.
A 26-year old patient consulted a dermatovenereologist, complaining of moderate mucous discharge from the urethra, colic during urination, usually in the morning. He relates the disease with unprotected sexual contact to a hardly familiar person 4 days ago. Which initial diagnosis is most likely?

A. Candidosis

B. Gonorrhea

C. Trichomoniasis✔

D. Mycoplasmosis

E. Ureaplasmosis

1. Confirmation of initial diagnosis.

2. Administration of treatment.


On examination of a patient, a dermatologist performs scraping of damaged skin region with glass slide. Which method of examination does a doctor use?

А) grattage; ✔

В) palpation;

С) diascopy;

D) curettage;

Е) three-glass test.

For which puprose is this method used?
Patient M., 59 years old, was referred to inpatient department complaining of tenderness in the oral cavity while talking and eating. The patient had been at the inpatient dentistry department with diagnosis: erosive stomatitis for two weeks. Improvement after treatment was not observed. Objectively: red erosions of various sizes are on the oral mucosa, on the periphery of which are present remnants of bullae coverings. Skin is clear. Initial diagnosis?

А. Pemphigus vulgaris ✔

В. Herpetiform dermatosis (Duhring’s disease)

С. Candidiasis

D. Exudative erythema multiforme

Е. Herpes

Which additional methods of examination should be performed to verify diagnosis?
A 67 year-old woman consulted a dermatologist complaining of rash on the skin of the shins, moderate itching. She has been suffering for 4 years, when rash appears from time to time on shins and back of the hands. She was treated with natural medications with slight improvement. Concomitant pathology – varicose diseases since 35 years. Objectively: foci have large-scalloped margins, distinctly separated from adjacent healthy skin with corneous layer of the epidermis, which sloughs off. Skin in the lesion regions is highly hyperemic, congestive bluish, slightly infiltrated, the surface has erosions resembling moist disc-like regions. Erosions are covered with a large number of thin, plate-like crusts-scales of yellowish-greenish color. The process is distributed in the periphery. Your initial diagnosis?

А. Erysipelas

В. Microbial eczema

С. Superficial chronic diffuse streptoderma ✔

D. Allergic dermatitis

Е. Pemphigus vulgaris

Plan of examination and treatment.
Patient, 39 years old, has been suffering from skin disease for 8 years. Rashes are constantly present on the skin of the elbows and knees. In winter, rashes are more generalized. Objectively: multiple bright red papular rashes with distinct margins are on the skin of the scalp, the trunk, and the extremities, the central surface of papulae is covered with silverish exfoliation. Your diagnosis?

А) extensive psoriasis, progressive stage, winter form; ✔

В) extensive lichen ruber planus, progressive stage;

С) extensive psoriasis, regressive stage, winter form;

D extensive psoriasis, progressive stage, summer form;

Е) limited lichen ruber planus, progressive stage.

Which diagnostic tests for making this diagnosis can you name and describe?
Patient M., 34 years old, complains of reddening of the face and arms, itching. She has been suffering for 3 weeks. The disease started after repair of apartment (contact with nitro dyes). On examination: hyperemis, edema, bullae, erosions on the arms, neck, face. What is initial diagnosis?

А. Simple contact dermatitis;

В. Acute eczema;✔

С. Urticaria;

D. Allergic contact dermatitis;

Е. Toxicodermia.

Conduct differential diagnostics of this disease.
A patient consulted a doctor complaining of pain during urination, discharge from the urethra. The complaints had been present for 5 days. Objectively: sponges of the urethra are hyperemic, swollen, purulent discharge in large amount. Urine in the first glass of two-glass test is diffuse-cloudy. In smears – leukocytosis, diplococci are located in pairs.

Your initial diagnosis?

А. Chlamydiosis

В. Gonorrhea ✔

С. Mycoplasmosis

D. Gardnerella infection

Е. Candidosis

1. Confirmation of initial diagnosis.

2. Tactics of treatment.
A female patient, 27 years old, presented with complaints of itching, rash on the trunk and upper extremities. Objectively: polygonal papulae with lustrous, wax-like surface are on the trunk, flexor surfaces of the forearms; umbilicate depression is visualized in the center of some elements. Initial diagnosis?

А) secondary syphilis;

B) psoriasis;

С) lichen ruber planus; ✔

Д) atopic dermatitis;

Е) tuberculosis papulonecrotica.

What is topical therapy for this disease?
A 37-year old woman consulted a dermatologist complaining of rash and moderate itching in the region of shins and thighs. Objectively: pustules with yellow-green content, interwoven with hair shaft, linear excoriations, erosions, crusts are present on the skin of the shins and thighs on slightly erythematous background. The symptoms appeared after depilation. Initial diagnosis?

А. carbuncle

В. deep ostiofolliculitis ✔

С. superficial trichophytosis

D. furuncle

Е. sycosis

Differential diagnosis. Treatment plan.

A 30-year old patient complains of rash on the face skin, itching, burning, pain in this region. He has been suffering for 1.5 years. Objectively: infiltrated foci of bright-red color, covered with pustules and crusts, with numerous erosions are observed on the skin of the face in the chin region. Submandibular lymph nodes are slightly swollen, movable, not merged with adjacent tissues.

Your initial diagnosis?

А. acne vulgaris

В. Parasytic sycosis

С. Recurrent herpes

D. contact dermatitis

Е. ordinary sycosis ✔

Conduct differential diagnostics
Patient R., 44 years old has been at the inpatient department with the diagnosis pemphigus vulgaris. Treatment has been prescribed: 60 mg of prednisolone. In which doses should prednisolone be distributed per day?

A. 4+4+4


B. 5+4+3

C. 7+3+2 ✔

D. 3+5+4

E. 8+3+1


Which additional medicines should be prescribed to this patient?
Patient 19 years old complains of the rash on the scalp, skin of elbow joints, exfoliation. The patient says he used anti-dandruff shampoo, but did not achieve improvement. Objectively: red papulae, covered with branny scales, are found on the border of the scalp and smooth skin, behind the ears, on extensor surface of elbow joints. A dermatologist performed palpation of rash on the scalp with closed eyes, in which he felt relief margins in the periphery of rashes. Identify the conducted diagnostic test:

А) Pilnov’s sign;

В) Koebner symptom;

С) Nikolsky’s symptom;

D) Kartamyshev’s symptom; ✔

Е) Auspitz sign.

For differential diagnostics of which dermatological disease is this test performed? (describe).
A 28-year old patient complained of colic during urination and discharge from the urethra, usually in the morning. From anamnesis, it is known that 6 days before the patient had accidental sexual contact with unfamiliar woman. He denies having other sexual contacts and he did not treat himself. The patient has been married for 4 years, has a 3-year old daughter. The last sexual contact with his wife was 2 days ago. Which diseases should be suspected first of all?

A. Syphilis, candidosis

В. Gonorrhea, trichomoniasis, chlamydiosis

С. Prostatitis, proctitis

D. Hepatitis B, C

Е. Mycoplasmosis, ureaplasmosis, Gardnerella infection

1. Your further tactics?

2. Which dispensary measures should be conducted first of all?
A patient consulted a dermatologist, complaining of rash on the neck skin, pain. Objectively: bright-red infiltrate with diameter 3 cm, swelling are on the skin of the nape of the neck. The infiltrate has an opening with pus discharge. In laboratory total blood analysis is leukocytosis, increased ESR. Which diagnosis is the most likely?

А. herpes

В. impetigo

С. furuncle ✔

D. carbuncle

Е. erysipelas

Compile treatment plan.
A patient, 39 years old, was admitted to dermatological department with diagnosis: Scabies. The diagnosis was made on the basis of detected following clinical signs, except:

А. Itching (in the evening, at night)

В. Specific localization of rash

С. Presence of itch pathways

D. Paired location of papulovesicular elements

Е. Absence of rash on the palms, soles, face, neck, skin of the scalp. ✔

Write out prescriptions of medicines for treatment according to Demyanovich.
A man 53 years old consulted a dermatologist complaining of rash appearance on the mucosa of the soft and hard palate, which interferes during eating, especially solids. On examination: distributed erosions of bright-red color, globular, without inflammatory reaction around them. Your diagnosis?

A. Pemphigus vulgaris ✔

B. Herpes

C. Candidiasis

D. Aphthous stomatitis

E. Herpetiform dermatosis (Duhring’s disease).

Which diagnostic tests should be performed to make a final diagnosis?
After having cold, the patient experienced rash on the skin of the trunk and extremities, accompanied by significant itching. Objectively: lenticular papular elements of bluish-red color with waxy surface and umbilicate depression in the center are visualized on the skin of the trunk, flexor surfaces of the forearms and shins. Your initial diagnosis?

А) psoriasis;

В) atopic dermatitis;

С) scabies;

D) lichen ruber planus; ✔

Е) Gilbert’s pityriasis rosea.

With which nosologies is this disease most often differentiated?
A patient with complaints of itching and rash on the skin, which had appeared 2 weeks before, consulted a dermatologist. On examination: grayish-white plaques, resembling lace, were observed on mucosa of the cheeks and lips; numerous polygonal lenticular papulae with lustrous surface and pinpoint depression in the center were on the skin of the forearms. Make diagnosis:

A) Lichen ruber planus; ✔

B) Psoriasis;

C) Secondary syphylis;

D) Candidosis;

E) Erythema multiforme.

Recommended treatment.
In a 10 years old girl, body temperature increased to 39.50C in 4 hours after aspirin intake. She complains of malaise, dizziness, rapid appearance of red spots and bullae on the skin, exfoliation of epidermis with formation of erosive surfaces. Lesions resembled second-degree burns. Which diagnosis is the most likely?

А. Acute epidermal necrolysis – Lyell’s syndrome;✔

В. Pemphigus vulgaris;

С. Erythema multiforme;

D. Ritter’s exfoliative dermatitis;

Е. Duhring’s disease (dermatitis herpetiformis);

Compile plan of a patient’s examination.
A 19-year old patient experienced redness and burning in the corner of the mouth, which appeared after visit to a dentist. Objectively: fissure, covered with yellow crust is in the right corner of the mouth. Skin around the site is of bright-red color.

Make initial diagnosis

А. streptococcal angular cheilitis ✔

В. pemphigus

С. herpetic infection

D. primary syphilis

Е. candidal stomatitis

Conduct differential diagnostics


A patient has noticed purulent discharge from the urethra, pain during and at the end of urinating, frequent voids to urination, frequent erections and pollutions for several days. Terminal hematuria is observed. Manifestations appeared in 7 days after sexual contact with a hardly familiar woman. Objectively: erythema and swelling of the external urethral canal. On palpation: the urethra is somewhat infiltrated, painful. In conduction of two-glass test – urine is cloudy in both portions. Which diagnosis is the most likely?

A. Fresh acute total urethritis✔

B. Fresh acute anterior urethritis

C. Fresh acute posterior urethritis

D. Chronic gonorrheal urethritis

E. Chronic chlamydial urethritis

1. Diagnostic tactics.

2. Treatment tactics.


Patient M., 55 years old, was admitted to inpatient department by sanitary aviation. On examination: the patient’s general condition – severe, active movements are complicated due to pain, t 38.30С, the mouth opens with difficulty, and remnants of hemorrhagic crusts are on vermillion border. Multiple extensive erosions, covered with dirty plague, with papillomatous growths are observed on the skin of the abdomen, in axillary, submammary, inguinal folds. Vesicles, bullae are on the periphery of lesion foci on the background of healthy skin. Nikolsky’s symptom is positive. Which dermatosis is meant in this case?

А. Eczema

В. Pemphigus ✔

С. Herpes zoster

D. Herpes

Е. Lichen ruber planus

With which diseases should differential diagnosis be performed?

In a woman, 26 years old, rash appeared on the skin of flexor surfaces of the upper and lower extremities, trunk, which is accompanied by intensive itching. Objectively: papulae, lichenifications are present on erythematous background. She has been suffering for 10 years. She links rash appearance with previous stressful situation. Which diagnosis is the most likely in this patient?

А. Eczema;

В. Psoriasis;

С. Contact dermatitis;

D. Allergic dermatitis;

Е. Neurodermitis.✔

Compile plan of examination and treatment for this patient.


Patient M., 19 years old, consulted a dermatologist complaining of skin itching, usually at night. She has been suffering for 8 days. Marked point papules, pustules, excoriations are observed on the skin of the hands, pustules and papulovesicles are located in pairs in abdominal region. Which diagnosis should be made?

А. Lichen ruber planus

В. Gilbert’s pityriasis rosea

С. Scabies ✔

D. Contact dermatitis

Е. Toxicodermia.

Conduct differential diagnostics of the disease.
An 18-year old patient was admitted to inpatient department complaining of rash on the face skin, pain, temperature 390C. Objectively: a dense, bright-red node is on the skin of the right cheek in the nasolabial region. Yellow-green necrotic shaft is seen through the opening of the node. Initial diagnosis?

А. scrofuloderma

В. furunculosis

С. carbuncle

D. furuncle ✔

Е. eczema

Treatment plan. Differential diagnosis
An 11-year old boy was admitted to hospital complaining of general weakness, rash on the skin, accompanied by itching. Objectively: grouped tight bullae, size from a pea to a hazel nut, filled with transparent content, are on the skin of the trunk, buttocks, femoroinguinal folds on erythematous background. The skin of the palms and soles is not affected. Eosinophilia in the blood. Initial diagnosis?

А. Pemphigus vegetans

В. Herpetiform dermatosis (Duhring’s disease) ✔

С. Pemphigus vulgaris

D. Seborrheic pemphigus

Е. Herpes

Which diagnostic tests should be performed to make final diagnosis?
A woman with multiple hollow rash elements, with yellow-green content, on the skin, visited a dermatologist. Which morphological element may it be?

А) pustule; ✔

В) macula;

С) papula;

D) vesicle;

Е) urtica.

Indicate basic differences between this element and bull.
A mother brought a 5-year old daughter to consult a dermatologist for rash on the face. Objectively: pale-pink spots of various sizes with distinct margins, covered with tiny scales, are on the face skin. She has been ill for 2 years, in summer spots disappear. Initial diagnosis?

А. vitiligo

В. pityriasis simplex

С. secondary hypopigmental spots

D. ringworm

Е. herpes simplex

Plan of treatment and examination.
A 67-year old patient complains of rash on the right shin, periodic tenderness in rash sites. Status localis: an ulcer, size 2x3 cm is in the focus, verrucous growths are on its periphery. Ulcer base is bleeding. On pressing, drops of thick pus discharge from small fistulous openings. The patient has been ill for 4 years. Initial diagnosis?

А. trophic ulcer

В. chronic ulcerous vegetative ✔

С. serpiginous nodular syphilid

D. verrucous form of skin tuberculosis

Е. chancre

Treatment plan. Differential diagnosis.
A patient complains of secretion from the urethra, accompanied by pain and colic during urination. Complaints appeared on the 3rd day after unprotected sexual contact with unfamiliar person. Objectively: glans penis is hyperemic and swollen, sponges of the outer orifice of the urethra are swollen. A large amount of yellowish-green pus discharges from the urethral canal.

Make initial diagnosis.

A. Ureaplasmosis

B. Trichomoniasis

C. Chlamydiosis

D. Fresh gonorrhea✔

E. Gardnerella infection

1. Substantiate initial diagnosis.

2. Diagnostic tactics.
A 54-year old man consulted a dermatologist, complaining of rash appearance on mucosa of the soft and hard palate, tenderness while eating solid food. On examination: bright red, round multiple erosions, without inflammatory reaction around. Your diagnosis?

A. Pemphigus vulgaris ✔

B. Herpes

C. Candidiasis

D. Aphthous stomatitis

E. Leukoplakia

Which additional methods of examination should be performed to confirm diagnosis?
A 45-year old woman was admitted to inpatient department complaining of general weakness, rash on the skin, accompanied by itching. Objectively: grouped tight bullae, size from a pea to hazel nut, filled with transparent content, are observed on the skin of the trunk, buttocks, femoroinguinal folds on erythematous background. The skin of the palms and soles is not affected. In general blood analysis – eosinophilia. Initial diagnosis?

А. pemphigus vegetans

В. Herpetiform Duhring’s dermatosis ✔

С. Pemphigus vulgaris

D. Seborrheic pemphigus

Е. Herpes

Compile treatment plan for this patient.
A patient, 45 years old, complains of appearance of nodular elements on the skin of the sacral area, upper and lower extremities. Rashes have tendency to peripheral growth and fusion, painless. He has been ill for 2 years. Exacerbation is observed usually in spring. It is known from anamnesis that his father suffered from similar skin lesion. Objectively: pathological elements include drop-like and nummular nodules, plaques, covered with white scales, which slough off easily. Your initial diagnosis?

A) Neurodermitis;

B) Lichen ruber planus;

C) Psoriasis; ✔

D) Pityriasis rosea;

E) Seborrheic eczema;

Technique of a patient’s examination for verification of diagnosis and differential diagnostics?
Patient K., 47 years old, was admitted to dermatological department after consultation with an infectious disease doctor. From anamnesis: complaints of skin itching, insomnia, decreased work capacity, irritability. The patient notices appearance of the mentioned symptoms after eating dishes containing sea fish. His condition rapidly worsened and rash spread to the skin of entire trunk, extremities after treatment of skin with 5% iodine solution. Dermatological condition: tough tiny vesicles, bullae and papules with a tendency to grouping are detected on the skin of the trunk and extremities. Nikolsky’s symptom is negative.

Which diagnosis may be made?

А. Pemphigus vulgaris

В. Duhring’s dermatosis ✔

С. Allergic dermatitis

D. Lichen ruber planus

Е. Mycosis of the mucous membranes

Describe your tactics of treatment of this patient.


Patient V., 50 years old, was admitted to dermatological department with diagnosis: pemphigus vulgaris. The basic therapy of complex treatment was administration of eight tablets of prednisolone per day. In which doses should prednisolone be distributed throughout the day?

A. 4+2+2

B. 4+4+0

C. 6+2+0


D. 3+2+2

E. 5+2+1 ✔

Which additional medicines should be prescribed to this patient?
A 2-month old boy was hospitalized into admitting department of pediatric hospital by ambulance team. He had been ill for 2 days, when body temperature rose to 38°С., nausea and diarrhea appeared, rash appeared 10 hours before on the skin around the mouth, umbilicus, anus, genitals. Status localis: large (approx. 1 cm in diameter) stiff bullae, moist erosions, positive Nikolsky’s symptoms are present in foci on the background of bright erythema. Initial diagnosis?

А. pemphigus vulgaris

В. Ritter von Rittershain exfoliative dermatitis

С. Duhring’s dermatitis

D. herpetic eczema

Е. streptococcal impetigo

Treatment plan. Differential diagnosis.
A mother with a girl consulted a dermatologist complaining of fever, irritability, insomnia, as well as pain in anogenital region, disorders of dysuria. On examination: diffuse hyperemia and swelling of labia majora and perineum. A large amount of purulent exudate discharges from the vagina. Crusts are on the skin of labia minora and majora. Inguinal lymph nodes are enlarged and painful. Which initial diagnosis can be made?

A. Chlamydial vulvovaginitis

B. Gonorrheal vulvovaginitis✔

C. Bacterial vulvovaginitis

D. Trichomonas vulvovaginitis

E. Vulvovaginitis

1. Confirmation of the initial diagnosis.

2. Further tactics.

Patient A, 33 years old, complains of skin itching on both hands. He has been suffering for 1.5 year. He links exacerbation of the disease with exposure to formaldehyde tar at work. Objectively: foci of damage are localized on both hands symmetrically. Along with erythema with indistinct margins are papulae, vesicles, erosions, crusts, scales. Which pathology is the most likely?

А. Allergic dermatitis;

В. Professional eczema; ✔

С. Microbial eczema;

D. Simple contact dermatitis;

Е. Erythema multiforme.

Compile plan of examination for this patient.
Boy D, 11 years old, complains of itching of the posterior neck surface. On examination: excoriations and redness are on the skin of the scalp. Dandruff is observed on the hair. Which disease may be suspected?

А. Psoriasis of the scalp

В. Scabies

С. Pityriasis rosacea

D. Pediculosis✔

Е. Lupus erythematosus

Prescribe treatment to this patient (Write out prescription of medicine).
Patient K., 60 years old, was admitted to inpatient department, complaining of tenderness in the oral cavity while talking and eating. The patient had been treated for erosive stomatitis for two weeks. Improvement after treatment was not observed. On examination: red erosions of various sizes are on the oral mucosa, on the periphery of which are present remnants of bullae coverings. Skin is clear. Initial diagnosis?

А. Pemphigus vulgaris ✔

В. Duhring’s herpetiform dermatosis

С. Candidiasis

D. Exudative erythema multiforme

Е. Herpes

Which additional methods of examination should be performed to confirm diagnosis?
A 58-year old woman was admitted to inpatient department complaining of rash on the skin of the trunk, itching and general weakness. Objectively: vesicles, bullae, and crusts with the tendency to grouping are on the skin of the abdomen, back and face. Pathohistological data: a bulla is subepidermal, eosinophilia is in the content of the bulla. Initial diagnosis?

А. Pemphigus vegetans

В. Herpetiform dermatosis (Duhring’s disease) ✔

С. Pemphigus vulgaris

D. Exudative erythema multiforme

Е. Herpes

Prescribe treatment to this patient.
Patient P., 51 years old, consulted a dermatologist complaining of appearance of bullae on oral mucosa and the trunk. The disease appeared unexpectedly. Objectively: bullae of a pea size, filled with serous content, are observed on unchanged skin and oral mucosa. Rashes are unstable. Erosions and crusts appear at their site. Your initial diagnosis?

A. Pyoderma

B. Herpetic dermatosis (Duhring’s disease)

C. Herpes

D. Exudative erythema multiforme

E. Pemphigus vulgaris ✔

Describe the most effective methods of verification of this diagnosis.
In a man, 45 years old, numerous inflammatory rash, consisting of pink-red papulae, covered with whitish scales in the centre, appeared gradually over 2 weeks on the skin of the scalp and trunk. Similar rash had appeared several years before in winter season, which gradually disappeared to the end of spring without treatment. Which diagnosis is the most likely?

A) Eczema;

B) Allergic dermatitis;

C) Contact dermatitis;

D) Psoriasis; ✔

E) Neurodermitis.

Which symptoms do you suggest for verification of diagnosis and with which pathohistological processes are they associated?
A patient, who came to the dispensary of skin and venereal diseases, was diagnosed with chronic gonorrheal urethroprostatitis, based on anamnesis data, typical clinical picture and results of laboratory investigation. What is the tactics of treatment of this patient if resistance to antibiotics is present?

A. Local methods of treatment

B. Sulpha drugs and immunostimulating therapy✔

C. Physiotherapeutic methods of treatment

D. Immunocorrecting and general strengthening therapy

E. Uroseptics of non-antibiotic choice

1. Substantiate your choice.

2. Give an example of prescribed therapy.


Patient B., 44 years old, was admitted to inpatient dermatological department, complaining of rash on the skin of the trunk, poor general condition. On examination: fatty crusts with underlying erosive surface are observed on the chest skin on erythematous background. Acantholytic cells are in impression smears from the base of erosions. Your initial diagnosis?


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